About KYPHI

KYPHI is a clinical neuro-cosmetic and luxury body care brand developed by Botanicsens Inc. under the scientific leadership of Professor Taesun Park (Yonsei University). Backed by over 40 years of academic research and patented aroma-signal technology, KYPHI targets the biological link between chronic sensory stress and dermal aging.

Unlike conventional cosmetics that sit on the epidermal surface, KYPHI relies on the 500 Dalton rule. It utilizes ultra-low molecular aromatic compounds (<200 Da)—specifically Undecane, α-Ionone, β-Ionone, and Dihydromyrcenol—that directly bind to olfactory receptors expressed in human skin cells:

• Barrier Regeneration: Patented Dihydromyrcenol stimulates the Akt signaling pathway to accelerate involucrin protein synthesis, fortifying the skin barrier against trans-epidermal water loss (TEWL).
• Anti-Stress & Cortisol Neutralization: β-Ionone suppresses dexamethasone/cortisol damage, protecting endogenous hyaluronic acid and collagen synthesis from stress-induced breakdown.
• Histamine Regulation & Itch Relief: Undecane inhibits mast cell degranulation, reducing histamine release by up to 53% to relieve severe dryness, irritation, and atopic discomfort.